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Coffee is widely consumed throughout the United States. Some prior studies have associated coffee consumption with increased rates of heart disease, whereas other studies have shown less heart disease in coffee drinkers.
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In this issue: Side effects of finasteride; new ruling on pharmaceutical companies paying generic manufacturers; and FDA actions.
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On 15 May the FDA Center for Biologics Evaluation and Research/Office of Blood Research and Review (CBER/OBRR) granted market clearance to the OraQuick in-home HIV-1/2 antibody test based on the recommendation of the Blood Products Advisory Committee.
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In this paper, the authors performed a pharmacoepidemiologic study on the relationship between azithromycin, a frequently used broad-spectrum macrolide antibiotic, and cardiovascular death. The authors analyzed data from the Tennessee Medicaid program.
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Sjogren's syndrome is an autoimmune condition that leads to chronic inflammation with salivary and lacrimal gland dysfunction. The diagnosis of Sjogren's often is delayed by several years because the initial presenting symptoms can be non-specific. However, some manifestations of Sjogren's may be life threatening, including brain damage and cancer. It is very important for the primary care physician to recognize the early signs and symptoms and to initiate the appropriate workup and treatment in coordination with consulting specialists to prevent further morbidity and mortality.
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In a matched cohort study involving immunocompetent individuals ¡Ý 60 years of age, the incidence of herpes zoster recurrence following a recent initial episode was low in both herpes zoster vaccine recipients and the unvaccinated. This low-risk questions the need for vaccinating immunocompetent adults with recent herpes zoster infections.
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