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The rabies symposium at the conference of the International Society of Travel Medicine in Vancouver, Canada, featured Drs. David Warrell, David Shlim, and Kanitta Suvansrinon.
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High-Dose Statin Therapy, Value for Older Adults; Simvastatin, Best for
Parkinson's Disease; Polyethylene Glycol for Chronic Constipation; FDA
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A multicenter non-inferiority open-labeled randomized controlled trial of oral amoxicillin-clavulanate (50 mg/kg/day divided 3 times a day for 10 days) compared to initial parenteral treatment with ceftriaxone (50 mg/kg/day as a single daily dose for 3 days) followed by oral amoxicillin-clavulanate (for 7 days) for children < 6 years of age with acute pyelonephritis and no anatomic urogenital tract abnormalities was conducted from 2000 to 2004 among 502 children 1 month to 7 years of age in 28 primary care practices in northern Italy.
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Synopsis: A large primary care pediatric study of recurrent urinary tract infections found a 12% per year recurrence rate with risk factors being white race, age 3-5 years, and grade 4-5 vesicoureteral reflux. Antimicrobial prophylaxis did not reduce the risk for recurrence but was associated with increased risk of recurrent infection caused by resistant organisms.
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There is no proven therapy for infection due to the mosquito-borne flavivirus West Nile Virus, introduced to a fully susceptible U.S. population in 1999.
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Guidelines for this years influenza season are now available, with important recommendations to hospitals and clinics.
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Patients receiving a probiotic yogurt drink were protected from antibiotic associated bacteria.
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Fully 95% of serum thyrotropin (TSH) measurements were normal in screening tests ordered by primary care physicians. Half of abnormal TSH labs became normal upon repeat measurement. If the initial TSH result was normal, there was only a 2% chance it would become abnormal within 5 years.