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Twice in the past 2 years I've encountered pulmonary histoplasmosis in travelers returning from Central America (Mexico and Costa Rica), and both times the diagnosis proved challenging. One case, in particular, was a 60-year-old man who had traveled to Costa Rica for 1 week and then presented with fever, persistent dry cough, malaise, and complaints of memory loss.
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Herpes zoster vaccine (Zostavax) was licensed in the United States in 2006 subsequent to the publication of the Shingles Prevention Study, a large (n = 38,546) prospective trial that demonstrated a 51% reduction in zoster and a 67% reduction in postherpetic neuralgia in vaccines compared to controls.
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Leptospirosis is a zoonosis caused by multiple serovars of bacteria in the genus Leptospira that are widely distributed in the tropics, as well as some subtropical and temperate areas.
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Admissions to a public hospital in kwazulu-natal, South Africa, for treatment of MDR- and XDR-TB from 2003 to 2008 were examined for health care workers (HCWs) compared with non-HCWs.
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In this issue: Anticholinergic drugs for COPD; pioglitazone for diabetes prevention; insulin degludec in Phase 3 trials; and FDA Actions.
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In this meta-analysis, individuals who exercised or had sex episodically had an increased risk of acute cardiac events during those activities compared with those who had high levels of habitual physical activity.
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Apixaban and rivaroxaban near approval for nonvalvular atrial fibrillation; fidaxomicin for C. difficile infections; guideline for intensive insulin therapy; and FDA Actions.
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Women who drink little or no coffee appear to be at an increased risk of stroke compared with those who drink moderate amounts of coffee.
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This study concluded that subjects without a known history of any cardiovascular disease who demonstrated ventricular premature complexes on a 2-minute rhythm strip are significantly more likely to die from sudden cardiac death and the effect appears to be additive when atrial premature complexes occur concurrently.
