Infectious Disease
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Genital HPV in Men: How Common Is It?
In this U.S. cross-sectional survey, the prevalence of genital human papillomavirus (HPV) infection in adult men was 45%, of which 25% were high-risk subtypes. The overall rate of HPV vaccination among those who were eligible was 11%.
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Dual Antibiotic Therapy Is Not Routinely Necessary for Uncomplicated Cellulitis
A randomized, multicenter, placebo-controlled clinical trial that enrolled patients presenting to emergency departments with uncomplicated cellulitis found the addition of trimethoprim-sulfamethoxazole to cephalexin did not lead to better outcomes.
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Is This 4:1 Flutter?
The rhythm in the figure was diagnosed as atrial flutter with 4:1 AV conduction. Do you agree? How would you confirm your answer?
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Clinical Briefs
In this section: treating hypothyroidism in seniors; revisiting penicillin allergies; and new diverticulitis guidance.
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Sofosbuvir, Velpatasvir, and Voxilaprevir Tablets (Vosevi)
Vosevi is indicated for the treatment of adult patients with chronic hepatitis C infection without cirrhosis or with compensated cirrhosis who are infected with genotype 1, 2, 3, 4, 5, or 6, and have been treated previously with a hepatitis C regimen containing an NS5A inhibitor.
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Eat Right, and Live
An improvement in diet over 12 years in middle-aged nurses and other health professionals resulted in a decreased risk of death.
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Glucose Self-monitoring Not Helpful for Non-insulin-treated Type 2 Diabetes
In this pragmatic randomized trial, self-monitoring blood glucose did not lead to lower hemoglobin A1c levels or improvement in health-related quality-of-life measures.
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Infectious Disease Alert Updates
Immediate Improvement in Childhood Vaccination; A Better Mosquito Trap; Can FMT Restore Gut Flora and Eliminate Resistant Pathogens?
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Infections Associated With Adventure Travel
Some adventure travel is associated with exposure to infectious pathogens. Some adventure-related illnesses can be prevented. Understanding the details of an adventure trip can help focus a differential diagnosis for ill returned travelers.
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Autochthonous Crimean-Congo Hemorrhagic Fever in Europe
Two patients with Crimean-Congo hemorrhagic fever acquired in Spain are reported. The index patient acquired infection from a tick bite, and the second patient was a nurse who cared for the index patient. The first patient died in the hospital with multi-system organ failure and was diagnosed at autopsy. The second patient recovered with supportive care and was treated with ribavirin, but it was unclear whether the use of ribavirin was helpful.