Browse Infectious Disease Topics Articles by Topic

Oral Antibiotics in Endocarditis: Hitting the Target

Pharmacodynamic/pharmacokinetic analysis of patients in the POET study provides understanding of the efficacy of intravenous-to-oral stepdown antibiotic therapy in patients with endocarditis.

Oral Penicillin Challenge Found to Be Noninferior to Skin Testing Followed by Oral Challenge in Low-Risk Patients with Reported Penicillin Allergy

A multicenter, randomized clinical trial that compared direct oral penicillin challenge in low-risk patients to skin testing followed by oral challenge found no significant differences. Direct oral penicillin challenge appears to be a safe and effective way to delabel a penicillin allergy.

Malaria Vaccination: Dangerous, Dubious, or Ready for Prime Time?

Malaria vaccination with the RTS,S/AS01 vaccine is safe and effective. Implementation of the four-dose vaccination regimen for young children in areas of moderate- and high-intensity malaria transmission is in progress — with the expectation that hundreds of thousands of lives could be saved each year.

Nirsevimab-alip Injection (Beyfortus)

Nirsevimab can be prescribed to prevent respiratory syncytial virus (RSV) lower respiratory tract disease in neonates and infants born during or entering their first RSV season.

U.S. Long COVID Strategy Takes Flight

HHS opens Office of Long COVID Research and Practice, NIH begins enrollment for key clinical trials.

Biden, Congress Transition to New Era of Pandemic Prevention

The White House Office of Pandemic Preparedness and Response Policy will take over the duties of the current COVID-19 and Mpox teams in August.

Infectious Disease Alert Updates

Transcatheter Aortic Valve Endocarditis; Daptomycin-Associated Eosinophilic Pneumonia: The Lyon Algorithm

Leprosy Cases with Possible Acquisition in the United States

Six patients in California were found to have leprosy in the absence of a known exposure.

A Comparison of Sequelae After Hospitalization with COVID-19, Influenza, or Sepsis

The incidence of most selected new-onset medical conditions did not significantly differ among those who had been hospitalized with COVID-19, influenza, or sepsis.

The Degree of Pyuria Can Help Determine Urinary Tract Infection in Elderly Women

Elderly women with a urinary tract infection had a higher median number of urinary leukocytes compared to uninfected controls, including those with asymptomatic bacteriuria. For 264 leukocytes/µL, the sensitivity and specificity of microscopy were 88%. Using the standard pyuria threshold of 10 leukocytes/µL gave a specificity of 36% and a sensitivity of 100%.