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Influenza activity has been relatively low thus far in the 2008-2009 season in the United States. However, of the influenza viruses isolated and tested to date, there is significant resistance among the influenza A (H1N1) viruses to the antiviral oseltamivir.
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In this issue: FDA warning on topical anesthetics; antipsychotics increase sudden cardiac death; the step up vs step down debate; treating pain, fatigue, mood, and sleep in fibromyalgia; FDA Actions.
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FDA approved for the treatment of acute bacterial skin and skin structure infections (ABSSSIs) caused by susceptible gram-positive organisms including Staphylococcus aureus (MRSA and MSSA), Streptococcus agalactiae, Streptococcus anginosus group, Streptococcus pyogenes, and Enterococcus faecalis.
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The emergence of chronic wasting disease, a transmissible spongiform encephalopathy in North American cervids, raises concern about potential transmission to humans, as has occurred elsewhere with bovine spongiform encephalopathy and vCJD.
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A clonal outbreak of a newly identified organism, Clostridium neonatale, occurred in association with necrotizing enterocolitis in a neonatal ICU.
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Murine typhus is an unusual infection and probably often overlooked. Outbreaks occur when there is migration of rats and mice into residential areas.
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This study compared the efficacy of several commercially available insect repellents. The topical application of compounds containing DEET was far more protective against mosquito bites than was application of products containing soybean oil or citronella.
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Orlistat in Overweight Patients with Type 2 Diabetes; Sleep Attacks in Patients Taking Dopamine Agonists; Probiotics in Prevention of AAD; Botulinum Toxin for Wrist and Finger Spasticity; Exercise in People with Fibromyalgia; Risk of Diabetes Among Patients with Schizophrenia
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A protease-inhibitor-based regimen containing lopinavir-ritonavir provided more durable antiviral efficacy than a similar regimen containing nelfinavir in treatment-naïve HIV-infected patients.