The Infection Risk of Acid-Suppressing Drugs; Is Rosuvastatin As Safe As Other Statins?; Which Estrogen Preparation is the Safest?; FDA Actions.
This multicenter prospective observational study reveals that transfusion practice in the critically ill has not changed in the past decade. 44% of ICU patients receive transfusions, and transfusions continue to be associated with worse clinical outcomes.
Post hoc analysis of 3 large multicenter trials of patients with acute coronary syndromes demonstrates a strong association between transfusion and mortality.
A new, and as of yet unpublished study, has raised increased concern about the relationship between rofecoxib (Vioxx), Mercks blockbuster COX-2 inhibitor, and cardiovascular events.
To avert a looming public health crisis with a unique set of underlying causes, Congress and the administration, including federal public health agencies, must act quickly to reinvigorate pharmaceutical investment in antibiotic research and development (R&D). Otherwise, doctors wont have drugs to protect Americans against antibiotic-resistant infections a rapidly growing and often deadly problem.
