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Levator myalgia is a prevalent condition in women presenting with pelvic floor symptoms and is associated with greater symptom bother. Fibromyalgia is associated with an increased risk of levator ani myalgia in women presenting with prolapse.
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In this cross-sectional survey of 333 women, the majority reported current pubic hair removal (87%), and two-thirds reported removing all their pubic hair. Most women (60%) had experienced at least one complication because of the removal, the most common complications being epidermal abrasions and ingrown hairs.
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The findings in a recent study in which investigators evaluated the relative contributions of pre-pregnant weight, weight gain in pregnancy, and the presence of gestational diabetes on the rate of large-for-gestational age fetuses has shed light on how this true complication of pregnancy can be diminished.
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Selective estrogen receptor modulators (SERMs) like tamoxifene and raloxifene are now well-established therapeutics, and new agents such as bazedoxifene and ospemifene have recently been introduced. These new agents have unique tissue-specific profiles that allow for a customization of therapeutic effect. In this review, the profiles of bazedoxifene and ospemifene will be compared and discussed relevant to their place in clinical practice.
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In this two-part insulin primer, the authors will explore all aspects of insulin therapy. The first article will review the currently available forms of insulin, their formulation, mechanisms of action, pharmacokinetics, and appropriate use in diabetes therapy. The authors will address the practical aspects of insulin therapy including when and how to start insulin, review titration regimens, and provide insight into selecting insulins to best match patient needs.
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The term thrombocytopenia refers to platelet counts < 150,000/microL, with severe thrombocytopenia defined as a count < 50,000/microL.
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Mean daily doses of up to 40 mg of prednisone equivalents and lengthy ICU stays were associated with impaired physical outcomes in patients who survived acute lung injury.
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In this retrospective study of extubation outcomes in five ICUs at a single medical center, patients extubated at night had no increase in adverse events and their mortality rates and lengths of ICU stay were lower.
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In this large prospective study of trauma patients, the most important factor associated with post-traumatic seizures was the presence of alcohol intoxication.
