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Reproducibility of complex proteomic signatures in detecting early stage ovarian cancer has proven to be a significant challenge in the field of biomarker discovery. Although early reports of proteomic profiling demonstrated near 100% sensitivity and specificity in discriminating ovarian cancer from non-cancer, the ability to reproduce these results across datasets has been difficult.
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The well-known mantra of primary ovarian cancer management is surgery. The procedure has modified little in the last 30 years as the goal in advanced cases has been cytoreduction and, in seemingly early cases, it has been accurate staging.
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Stopping Aspirin Before Surgery; The Sponge Returns; Preventing Metabolic Syndrome; FDA Actions.
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The chances that a surgical patient in a U.S. hospital will receive appropriate antibiotic prophylaxis with drugs both administered and discontinued in a timely fashion remains essentially a flip of the coin.
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Emerging as the bane of cruise ships and nursing homes, norovirus with its ability to cause severe gastroenteritis, persist in the environment, and spread via contaminated food or human contact would seem to be the perfect candidate for a nosocomial pathogen of the most troublesome variety.
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Health care epidemiologists are reporting an increase in bloodstream infections (BSIs) due to the use of needleless mechanical valve devices that connect to central venous catheters.
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