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Polypharmacy is the simultaneous use of multiple medications. Many authors have defined polypharmacy as the simultaneous use of at least five or six medications. Others have suggested that polypharmacy should not be determined by the absolute number of medications, but rather the use of even a single medication that is not clearly indicated.
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Tamoxifen and CYP2D6 inhibitors, FDA Actions, and FDA Warnings.
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This issue is the second installment in a two-part series on breast cancer. The first part covered epidemiology, histologic types of breast cancer, screening, diagnosis, principles of treatment, and surgical management. This issue will cover chemotherapy, radiation therapy, endocrine therapy, metastatic breast cancer, and primary care for the breast cancer survivor.
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Comparing blood pressure medications, determining optimal length of androgen-deprivation therapy, red yeast rice for LDL reduction, and FDA Actions.
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The role of intensive antiplatelet therapy for prevention of vascular events in patients with atrial fibrillation remains controversial. The Atrial Fibrillation Clopidogrel Trial with Irbesartan for Prevention of Vascular Events (ACTIVE) trio of studies is an attempt to clarify this issue.
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A randomized study of treatment of septic arthritis in children 3 months to 15 years of age demonstrated that 10 days of treatment, with an initial 2-4 days intravenously followed by oral therapy, was sufficient for most cases, regardless of the infecting pathogen or site of infection.
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Adenovirus 14 (Ad14) has emerged as a cause of febrile respiratory illness (FRI) and has resulted in pneumonia in a significant number of patients.
