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Pediatric head trauma is one of the most common presenting complaints to the emergency department (ED).
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Laboratory studies and clinical data support the concept that prolonged mechanical ventilation (PMV) can induce or worsen lung injury, via activation of inflammatory mediators and/or microvascular fibrin deposition, processes that may be ameliorated by heparin.
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In this study from the Mayo Clinic in Rochester, MN, Herasevich et al tested an electronic algorithm that incorporated patient characteristics and ventilator data and notified clinicians immediately when potentially injurious ventilator settings were being used.
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Due to its lack of cardiovascular side effects, the short-acting non-barbiturate sedative, etomidate, has been one of the primary agents used to sedate hypotensive patients during rapid-sequence intubation (RSI).
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Hyponatremia is frequently seen in patients with left ventricular failure and has recently been shown to be associated with right ventricular dysfunction and worse outcomes in patients with pulmonary hypertension.
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In this issue: Statins and liver function; dosing timing for thyroxine; rivaroxaban for VTE, DVT, and stroke; echinacea and the common cold; and FDA actions.
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Anaphylaxis is a rapid-onset and potentially life-threatening allergic reaction.
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