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By William T. Elliott, MD
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The authors concluded that in a diverse, community-based population with new systolic heart failure, spironolactone did not reduce death or hospitalization, but did increase the incidence of hyperkalemia.
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Among patients with mild-to-moderate Alzheimer's disease, 2000 IU/d of vitamin E resulted in a slower functional decline and a decrease in the caregiver burden.
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A second sodium-glucose cotransporter 2 (sglt2) inhibitor has been approved for the treatment of adults with type 2 diabetes mellitus. These agents increase glucose secretion by inhibiting reabsorption in the kidney. Renal glucose threshold can be lowered to 70-90 mg/dL from a norm of 240 mg/dL in patients with diabetes. Dapagliflozin follows canagliflozin as the second SGLT2 approved and is marketed by Bristol-Myers Squibb and AstraZeneca as Farxiga.
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Resveratrol has substantial potential to improve health in different ways based on the research.
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This systematic review and meta-analysis investigated the effects of vitamin D supplementation on bone mineral density (BMD) and found no significant effect of vitamin D supplementation on the hip or spine and a small and significant increase in femoral neck BMD.
