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FDA eyes LNG ECP label change in light of research on weight impact

Labeling for the European levonorgestrel (LNG) emergency contraceptive pill NorLevo has been revised due to data indicating lower drug efficacy in women weighing 165 pounds and above. This move has led U.S. regulators to assess data on similar products.

Multipurpose methods show research advances

Strides are being made in development of multipurpose prevention technologies, defined as a single product or strategy configured for at least two sexual and reproductive health prevention indications: unintended pregnancy, HIV, and other sexually transmitted infections.

How to address deaths from ovarian cancer

A woman in her late 40s dies less than a year after ovarian cancer is diagnosed. She has three daughters ranging from 15 to 25 years of age. How can ovarian cancer be prevented in these three young women? How can ovarian cancer be prevented during the lifetime of ANY woman, whether or not she has a family history of ovarian cancer?

Bariatric Surgery: Does It Affect Pregnancy Outcomes?

In this large, retrospective cohort study, women with a history of bariatric surgery were at a small increased risk of both spontaneous and medically indicated preterm birth and small for gestational age births.

Pelvic Radiation in Endometrial Cancer:Are We Cutting Off Our Nose to Spite Our Face?

Long-term complications, particularly secondary cancers, were significantly more common in patients receiving whole pelvic radiation (vs brachytherapy alone) for early-stage endometrial cancer.

Emergency Contraception: A Copper IUD May Be the Best Choice

Women presenting for emergency contraception were offered a copper IUD or Plan B. Those who chose an IUD had a lower cumulative risk of unintended pregnancy at 1 year.

Surgical Excision of Endometriomas and Effect on Ovarian Reserve

In a prospective cohort study, women with endometriomas (> 2 cm) were found to have a decrease in ovarian reserve parameters compared to healthy controls 1 and 6 months after the endometriomas were removed.

Adding to Survival ( Again): Cervix Cancer

Bevacizumab added to chemotherapy, particularly paclitaxel and cisplatin, was efficacious in all response outcomes (objective response, progression-free survival, and overall survival) without diminution in quality of life or unacceptable toxicity.

Annual Mammography Screening: The Debate Continues

Although annual screening mammography did increase the detection rate of non-palpable tumors, it did not reduce mortality from breast cancer over 25 years of follow-up.

Continuous Use of Non-androgenic OC Improves Endometriosis Pain and Endometrioma Reoccurrence

Compared to cyclic use, a drospirenone-containing oral contraceptive pill used in a continuous fashion after the removal of an endometrioma is associated with a reduction in dysmenorrhea, non-menstrual pelvic pain, and reoccurrence of endometrioma formation.