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These 2 clinical trials comparing Standard and New Antiepileptic Drugs (SANAD) showed that for partial epilepsy, lamotrigine was clinically better than carbamazepine, and that for generalized and unclassifiable epilepsy, valproate was better tolerated than topiramate and more efficacious than lamotrigine.
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IVIG is safe and effective for worsening MG, but has no effect on the natural course of Miller Fisher syndrome.
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Many patients with Parkinson disease have normalization of movement during REM sleep, similar to the beneficial effects of levodopa while they are awake.
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Occipital nerve stimulation appears to decrease the cluster pain and attack frequency in most, but not all, patients with chronic drug-resistant cluster headaches.
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Compared with a lower dose, intensive treatment with atorvastatin in patients with stable coronary disease significantly reduces hospitalizations for HF.
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Obesity and the magnitude of nocturnal oxygen desaturation, which is an important pathophysiological consequence of OSA, are independent risk factors for incident AF in individuals <65 years of age.
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Elimination of daily routine CXRs reduced the number of CXRs in a mixed medical-surgical ICU, while not affecting readmission rate and ICU and hospital mortality rates.
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Current AP schedules do not appear to prevent catheter-related thrombosis. Systemic VTE and mortality, however, appeared lower after prophylaxis.
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Compared with a lower dose, intensive treatment with atorvastatin in patients with stable coronary disease significantly reduces hospitalizations for HF.
