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The meta-analysis by Vink and colleagues demonstrates that patients with either aortic or mitral valve replacement will benefit from high-intensity VKA therapy.
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In heterozygous familial hypercholesterolemia patients, rosuvastatin produced significantly greater reductions in LDL cholesterol, increases in HDL cholesterol, beneficial changes in other lipid values, and achievement of NCEP cholesterol goals than observed with equivalent doses of atorvastatin, with a similar adverse event profile.
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Since the results of the Womens Health Initiative randomized trials, many fewer postmenopausal women are using estrogen to control hot flashes. Alternatives include progesterones, antidepressants in low doses, caffeine avoidance, exercise, phytoestrogens, and black cohosh.
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A once-a-day dose of a valacyclovir reduces the rate of transmission of genital herpes (HSV-2) from an infected partner to an uninfected susceptible partner, according to a new study.
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A once-a-day dose of a valacyclovir reduces the rate of transmission of genital herpes (HSV-2) from an infected partner to an uninfected susceptible partner, according to a new study.
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Stiell and associates, convinced that the National Emergency X-Radiology Utilization Study Low-Risk Criteria rule leads to unnecessary testing and delayed triage of patients in the ED, developed the Canadian C-Spine Rule to assess alert, stable patients for traumatic cervical spine injury.
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Fourteen consecutive patients with sciatica were enrolled in this open-label trial of lamotrigine to determine its efficacy in pain control and its dose response curve.
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There are considerable anecdotal data suggesting that melatonin may improve sleep. Singer and colleagues carried out a trial of 2 sustained-release doses of melatoninone moderately high dose of 10 mg and one moderately low dose of 2.5 mg.
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Sulfonamide Antibiotics and Sulfonamide Nonantibiotics; Autoantibodies Before Onset of SLE; Prevention of VTE with Ximelagatran; Combined Levothyroxine Plus Liothyronine Compared to Levothyroxine Alone in Primary Hypothyroidism; Specific Site Involvement in Fixed Drug Eruption; Anticoagulation Therapy for Stroke Prevention in Patients with Atrial Fibrillation
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