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This issue is the second installment in a two-part series on breast cancer. The first part covered epidemiology, histologic types of breast cancer, screening, diagnosis, principles of treatment, and surgical management. This issue will cover chemotherapy, radiation therapy, endocrine therapy, metastatic breast cancer, and primary care for the breast cancer survivor.
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Comparing blood pressure medications, determining optimal length of androgen-deprivation therapy, red yeast rice for LDL reduction, and FDA Actions.
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The role of intensive antiplatelet therapy for prevention of vascular events in patients with atrial fibrillation remains controversial. The Atrial Fibrillation Clopidogrel Trial with Irbesartan for Prevention of Vascular Events (ACTIVE) trio of studies is an attempt to clarify this issue.
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A randomized study of treatment of septic arthritis in children 3 months to 15 years of age demonstrated that 10 days of treatment, with an initial 2-4 days intravenously followed by oral therapy, was sufficient for most cases, regardless of the infecting pathogen or site of infection.
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Adenovirus 14 (Ad14) has emerged as a cause of febrile respiratory illness (FRI) and has resulted in pneumonia in a significant number of patients.
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The combination of aspirin with clopidogrel is better than aspirin alone in reducing the risk of stroke in patients with atrial fibrillation.
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The differential diagnosis of acute chest pain includes three entities that can be lethal if missed: myocardial infarction (MI), pulmonary embolus, and aortic dissection.
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Primary percutaneous coronary intervention (PCI) results in more complete reperfusion of the infarct artery and lower rates of re-occlusion than fibrinolysis in patients with ST elevation myocardial infarction (STEMI). However, primary PCI is not performed at all centers, and fibrinolysis is still in widespread use.
