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Talk with women about pelvic pain — A high number might be going untreated
Results from a study by researchers at the National Institutes of Health and the University of Utah School of Medicine, Salt Lake City suggest a high proportion of reproductive-age women might be experiencing pelvic pain that goes untreated.
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Results of survey indicate unmet need for family planning at community health centers
Results of a recent survey at U.S. community health centers indicate an unmet need for more comprehensive family planning services at such facilities, according to a report issued by the Geiger Gibson /RCHN Community Health Foundation Research Collaborative and the Jacobs Institute of Women’s Health, all in Washington, DC.
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Oral contraceptives reduce the risk of developing endometrial cancer
Taking oral contraceptives, even for just a few years, offers significant long-term protection against endometrial cancer, confirms a detailed re-analysis of all available evidence by British researchers. Data indicate that the longer a woman takes oral contraceptives, the greater her reduction in risk for the disease, the analysis states.
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FDA approves first treatment for sexual desire disorder
The FDA has approved Addyi (flibanserin, Sprout Pharmaceuticals, Raleigh, NC) to treat acquired, generalized hypoactive sexual desire disorder in premenopausal women. The drug is the first such treatment to be approved by the FDA for this condition.
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Biomarkers of Intrathecal Inflammation in Multiple Sclerosis and Other Disorders
A study of intrathecal immune markers in neuro-immunological diseases revealed increased numbers of activated T and B cells in both relapsing and progressive multiple sclerosis, but they were preferentially embedded in the brain tissue in progressive multiple sclerosis.
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Cerebrospinal Fluid Tau and Amyloid-ß1-42 in Patients with Dementia
In patients with clinically diagnosed dementia, the CSF biomarker profile of low CSF amyloid-ß1-42, high total tau, and high phosphorylated tau was seen in the majority of patients with clinically diagnosed Alzheimer’s disease. Substantial proportions of patients with non-Alzheimer’s dementia were also found to have the Alzheimer’s disease pathological profile. The value of CSF biomarker measurements in clinical practice is uncertain.
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Vitamin D and Diabetic Neuropathy
Vitamin D deficiency may exacerbate the clinical manifestations of diabetic neuropathy, and supplementation with vitamin D3 may be beneficial.
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The Expanding Role of Tau in Neurodegeneration: New Insights from Huntington’s Disease
Although Huntington’s disease is due to a triplet repeat expansion in the huntingtin gene, this study demonstrates abnormally phosphorylated tau pathology in Huntington’s disease brain tissue.
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Small Fiber Neuropathy in Critical Illness
The spectrum of critical illness polyneuropathy may include painful, small-fiber degeneration that can be readily diagnosed by punch skin-biopsy.
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Fibromyalgia and Other Soft Tissue Pain Syndromes
MONOGRAPH: Sometimes it's helpful to ask the patient, “Do you have anywhere on your body that doesn’t hurt?”