Clinical
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Vitamin D and Diabetic Neuropathy
Vitamin D deficiency may exacerbate the clinical manifestations of diabetic neuropathy, and supplementation with vitamin D3 may be beneficial.
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Nutrition Therapy for Hypertension Using the Nitric Oxide Pathway
Daily one-time ingestion of inorganic nitrate from beet juice consistently lowered blood pressure in hypertensive patients by an amount comparable to single-drug therapy.
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Intensification of Oral Therapy for Type 2 Diabetes
ABSTRACT & COMMENTARY: It may not be relevant to primary care physicians. Here's why.
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FDA Actions
FDA strengthens warning about canagliflozin, approves cariprazine to treat schizophrenia and bipolar disorder, and green lights insulin degludec, a new long-acting insulin analog.
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Spironolactone Effective Add-on for Resistant Hypertension Patients
Spironolactone was the most effective add-on drug for treatment of resistant hypertension, suggesting that sodium retention plays a role in this condition.
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Study: Delay Shingles Vaccine to Age 60
The shingles vaccine does not represent a good value for patients at age 50 years, according to generally accepted standards.
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CDC Issues New Guidelines for Pneumococcal Vaccines
The time interval between the two vaccines improves the immune response.
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Diabetes Drug Reduces Heart Failure, Cardiovascular Death Risk
Patients with type 2 diabetes at high risk for cardiovascular disease who received empagliflozin had significantly lower rates of the composite cardiac vascular outcome and death from any cause.
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Research eyes use of tenofovir to impact herpes
The race is on to prevent the spread of herpes simplex virus type 2 infection, the most common cause of genital ulcer disease. In 2012, about 417 million sexually active adults ages 15-49 years had an existing prevalent HSV-2 infection.
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Planned Parenthood controversy spurs attacks on family planning funding
The often-quiet summer months in Washington, DC, were roiled this year by videos attacking Planned Parenthood Federation of America and its affiliates for facilitating the donation of fetal tissue at the request of some women having an abortion. The organization has strongly denied any wrongdoing, and multiple state investigations have turned up no evidence that it has profited off of such donations or otherwise violated the law.