Clinical
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Migraine with Aura and Systemic Right-to-Left Shunt: Risk for Stroke?
Right-to-left shunts, as detected by transcranial Doppler, are more common in patients with migraine with aura, but are not correlated with increased risk of silent posterior circulation infarcts or white matter lesions on MRI.
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Noninvasive Diagnosis of Transthyretin Amyloid Cardiomyopathy
A testing strategy combining bone scintigraphy and laboratory testing allows accurate diagnosis of transthyretin amyloid cardiomyopathy without the need for a biopsy.
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Can MRI Diagnose Myocarditis?
New quantitative MRI technique performs better than the older Lake Louise criteria for diagnosing myocarditis as compared to the standard of endomyocardial biopsy.
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Atrial Fibrillation Ablation in Heart Failure Patients May Be Particularly Beneficial
Atrial fibrillation ablation leads to better outcomes in heart failure patients compared to amiodarone.
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Rivaroxaban in the Real World
A large Phase IV registry study shows that rivaroxaban is associated with a very low incidence of major bleeding, death, or stroke. Also, adherence to therapy was much higher than observed in other studies with vitamin K antagonists.
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New Analysis of COGENT Data Supports Proton Pump Inhibitor Benefit
It shows comparable risks of gastrointestinal and cardiovascular events between low- and high-dose aspirin.
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Pediatric Seizures
Although benzodiazepines remain the first-line therapy, awareness of next steps in therapy is necessary.
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In Memoriam
On May 4, 2016, Dan Mishell, MD, passed away at home surrounded by family.
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Vulvar Squamous Intraepithelial Lesions
The International Society for the Study of Vulvovaginal Disease adapted Lower Anogenital Squamous Terminology to the specifics of the vulva and released the 2015 terminology. Vulvar Low-grade squamous intraepithelial lesion is benign and includes HPV effect and flat condyloma. Vulvarhigh-grade squamous intraepithelial lesion is the usual HPV-associated type of high-grade vulvar intraepithelial neoplasia and the non-HPV-associated type is labeled differentiated-type vulvar intraepithelial neoplasia.
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Colpocleisis: Body Image, Satisfaction, and Regret at 24 Week
Colpocleisis is an effective surgical treatment for pelvic organ prolapse. Women report high satisfaction and low regret.