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Percutaneous Coronary Interventions in Nonagenarians
Nonagenarians can undergo percutaneous coronary interventions with low in-lab complication rates, but 30-day and one-year mortality is considerably higher than in younger patients.
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Palliative Care-based Intervention Improves Quality of Life in Chronic Heart Failure
Among patients with advanced heart failure, implementation of an interdisciplinary palliative care intervention was associated with improved quality of life.
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Advance Care Planning Must Advance Forward
In a systematic review of 795,909 people in 150 studies, researchers found many Americans have not completed an advance directive.
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Clinical Briefs
In this section: diagnosing pulmonary embolism; tackling early prostate cancer; and treating urinary tract symptoms.
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Glecaprevir and Pibrentasvir Tablets (Mavyret)
The FDA has approved a dual fixed-dose combination of glecaprevir, a NS3/4A protease inhibitor, and pibrentasvir, a NS5A inhibitor, for the treatment of all major genotypes (1-6) of chronic hepatitis C infections.
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Genital HPV in Men: How Common Is It?
In this U.S. cross-sectional survey, the prevalence of genital human papillomavirus (HPV) infection in adult men was 45%, of which 25% were high-risk subtypes. The overall rate of HPV vaccination among those who were eligible was 11%.
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Dual Antibiotic Therapy Is Not Routinely Necessary for Uncomplicated Cellulitis
A randomized, multicenter, placebo-controlled clinical trial that enrolled patients presenting to emergency departments with uncomplicated cellulitis found the addition of trimethoprim-sulfamethoxazole to cephalexin did not lead to better outcomes.
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Separating Celiac Disease From Non-celiac Gluten Sensitivity
As there is no diagnostic test to confirm any patient’s 'non-gluten celiac sensitivity,' debate on the issue continues.
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Azithromycin Reduces Asthma Exacerbations
Asthma exacerbations essentially are induced exclusively by viral infections (as well as thermal and atopic stimuli). Is it time to reconsider that posture?
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BCG Vaccinations and the False-positive Effect
Clinicians should consider that the bacille Calmette-Guerin vaccination effect could influence tuberculin testing responsivity for an essentially indefinite period.