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Glucose Metabolism and Coronary Heart Disease in Patients with Normal Glucose Tolerance; Evidence of Airborne Transmission of the Severe Acute Respiratory Syndrome Virus; Alcohol Intake and Risk of Incident Gout in Men; Prevention of Strokes by Successful Carotid Endarterectomy in Patients without Recent Neurological Symptoms; Cox-2 Inhibitors vs Nonselective NSAIDs and CHF Outcomes in Elderly Patients; Interventions for the Prevention of Falls in Older Adults.
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The bivalent HPV vaccine was efficacious in prevention of incident and persistent cervical infections with HPV-16 and HPV-18, and associated cytological abnormalities and lesions. Vaccination against such infections could substantially reduce incidence of cervical cancer.
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Cantor and Baum, lawyers from the Yale University School of Medicine, have written an op-ed piece in the New England Journal of Medicine focusing on the central role of pharmacists in providing emergency contraception.
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GEMINI Trial; CAMELOT Trial; INVEST Trial; The Dangers of Vitamin E; FDA Actions.
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Raloxifene treatment of postmenopausal women with osteoporosis is associated with a lower incidence of estrogen receptor-positive invasive breast cancer.
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This study demonstrates that a sequential screening program that provides patients with first-trimester results and offers the option for early invasive testing or additional serum screening in the second trimester can detect 98% of trisomy 21-affected pregnancies. However, such an approach will result in 17% of patients being considered at risk and, hence, potentially having an invasive test.
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Abdominal fat increases with advancing age and has been linked to increased risk for diabetes and cardiovascular disease. While insufficient exercise and overeating certainly contribute to age-related acquisition of abdominal fat, hormonal and metabolic factors also have been implicated. Even thin individuals who exercise regularly display increased abdominal fat as they age.
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The first head-to-head comparison study of an ACE inhibitor and an angiotensin receptor blocker, to assess renoprotective effects in type 2 diabetes, has shown that the drugs are comparable in their benefit.
