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Exenatide (Extendin-4) significantly lowered HbA1C and caused weight loss in type 2 diabetes patients.
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Night sweats, day sweats, and hot flashes occur frequently in the elderly and are more closely associated with common ailments than serious illnesses.
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The consequences of sleep deprivation, as measured in otherwise healthy men, include elevations of sympathetic activity, increased levels of cortisol, and altered glucose metabolism.
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Effective weight loss was achieved in morbidly obese patients after undergoing bariatric surgery. A substantial majority of patients with diabetes, hyperlipidemia, hypertension, and obstructive sleep apnea experienced complete resolution or improvement.
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The National Cholesterol Education Program, a product of a collaboration of the National Heart, Lung, and Blood Institutes, the American College of Cardiology, and the American Heart Association, has updated its clinical practice guideline on cholesterol management.
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The hundreds of presentations at this meeting provided encouraging evidence that existing Alzheimers therapies may have greater benefits than first realized, and that a new generation of potential disease-modifying therapies for AD may be on the way.
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It seems prudent to strongly consider use of melatonin in our cognitively delayed patients with disordered sleep, but to monitor those with epilepsy very closely for exacerbation, and withdraw the drug.
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These studies provide additional data about the higher risk of relapse, and the greater potential for progression of disability following childbirth.
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Absence of evidence-based medicine is both humbling, as well as a reminder of how substantial a role the art and oral tradition of medicine plays in the care of neurologic patients.