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  • Long-Term Outcomes with Bare Metal Stents

    Doyle and colleagues performed a retrospective study of a large cohort of patients undergoing PCI at the Mayo Clinic from 1994 to 2000, to determine the long-term outcomes of BMS, with a focus on stent thrombosis and ISR.
  • Stroke and Infective Endocarditis

    The appropriate treatment of infective endocarditis (IE), to avoid embolic stroke, is unclear. Thus, Dickerman and colleagues explored the International Collaboration on Endocarditis Prospective Cohort Study (ICE-CPS) database to define the temporal occurrence of stroke in relation to antibiotic therapy.
  • Patent Foramen Ovale and Cryptogenic Stroke

    Patent Foramen Ovale (PFO) has been associated with cryptogenic stroke in young individuals, but the association is less clear in older individuals where other causes of stroke predominate.
  • Pharmacology Watch

    Rosiglitazone (Avandia) implicated in yet another study; Prilosec and Nexium not associated with cardiac events; Anastrozole (Arimidex) shown more effective than tamoxifen for treatment of early-stage breast cancer; antibiotics show no effect on sinusitis; FDA actions.
  • Diagnosing UTI is as Simple as 1, 2, 3

    Three criteria identify women who would benefit from empiric antibiotics for cystitis.
  • Nebivolol Tablets (Bystolic™)

    The FDA has approved another beta-adrenergic blocker.
  • Clinical Briefs by Louis Kuritzky, MD

    Testosterone in Older Men: Is Low Normal Too Low?, CT Pulmonary Angiography as Good as Ventilation- perfusion Scanning for Suspected Pulmonary Embolus, Vertebral Fracture Begets Vertebral Fractureand
  • ECG Review: Chest Pain After Bypass

    The 12-lead ECG and lead II rhythm strip in the Figure were obtained from a 59-year old man several days after coronary bypass. He complained of postitional chest pain. How would you interpret his ECG given this clinical context?
  • Pharmacology Watch

    Rosiglitazone (Avandia) implicated in yet another study; Prilosec and Nexium not associated with cardiac events; Anastrozole (Arimidex) shown more effective than tamoxifen for treatment of early-stage breast cancer; antibiotics show no effect on sinusitis; FDA actions.
  • The Long-term Risk for Fatal Pulmonary Embolism after Discontinuing Anticoagulant Therapy for Venous Thromboembolism

    Patients with a first VTE event occurring in association with a reversible or time-limited risk factor should be treated with anticoagulants for at least three months, whereas patients with a first PE should be treated for at least six to 12 months; in fact, a case can be made for indefinite anticoagulant therapy in PE patients who have a great concern about recurrent PE and/or who are minimally concerned about the bleeding risk of anticoagulant therapy and the need for frequent determinations of the INR.