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In This Issue: Baxter Bioscience has developed a whole-virus, two dose vaccine against avian flu; warning label now on antipsychotics regarding an increased risk of mortality in elderly patients treated for dementia-related psychosis; vitamin D for men with heart disease on horizon? A new oral anticoagulant may soon be available for prevention of thrombotic complications of hip or knee surgery; FDA Actions
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Doxorubicin-based chemotherapy has remained a standard for the treatment of soft tissue sarcoma for decades. Recently, combination gemcitabine and docetaxel demonstrated significant clinical activity in a single-institution mixed population study of women with uterine leiomyosarcoma.
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Oral Prednisolone for Acute Gout; Adding Aliskiren to Losartan for Diabetic Nephropathy; Early Aggressive Therapy in Type 2 Diabetes Pays Off; Sublingual Immunotherapy; Methylnaltrexone for Opioid-Induced Constipation; Prucalopride for Severe Constipation
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The impact of 7-valent pneumococcal conjugate vaccine (PCV7) was studied using the Nationwide Inpatient Sample, which is the largest source of inpatient data in the United States and drawn from about 1000 community hospitals.
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A retrospective, cohort study of 200 episodes randomly selected from 315 episodes, during 2000-2003, at Children's Hospital of Philadelphia, of laboratory-confirmed bloodstream infections among out-patient children with central venous catheters was performed to determine the optimum duration of antibiotic therapy before infection could be reliably excluded.
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In this study, 100 consecutive patients, who were receiving several different cytotoxic chemotherapy regimens for a variety of cancers, were self-referred on the basis of perception of mucositis, elevated temperature at home, malaise, or were referred by a nurse based on assessment of potential infection or mucositis.
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A blinded, prospective, case-control study of 40 children meeting all of the DSM-IV criteria for PANDAS matched with 40 children with obsessive-compulsive disorder and/or a chronic tic disorder was conducted with periodic intensive laboratory testing for group A streptococcus for 2 years, especially with clinical exacerbations or acute illness.
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For this study, 279 patients from five groups (including 70 with proven or probable invasive pulmonary aspergillosis, 27 patients with blood cultures positive for a fungal pathogen, and 20 with PCP) were BG levels were measured with the Fungitell test kit.
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In This Issue: Shingles vaccine added to CDC list of vaccines for adults 60 and older; CDC recommends Tdap for postpartum women; new study suggests sequential therapy with antibiotics for H. pylori may be more effective than standard therapy; FDA Actions.
