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In an intent-to-treat analysis, the use of conjugated equine estrogen combined with continuous medroxyprogesterone acetate by menopausal women increased the hazard ratio of invasive breast cancer to 1.24.
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The data in this case-control study of combined estrogen plus progestin therapy revealed an increased risk of breast cancer, particularly invasive lobular tumor, regardless of whether the progestin component was taken sequentially or continuously.
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Birth weight discordancy of > 15% for same sex and > 30% for different sex confer greatest risk of adverse perinatal outcomes in the absence of abruption.
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Following radiation therapy, adjuvant extrafascial hysterectomy decreased the risk of relapse for patients with bulky stage IB cervical cancer without improving survival.
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The vasomotor flush is viewed as the hallmark of the female climacteric, experienced to some degree by most postmenopausal women. In the Massachusetts Womens Health Study, the incidence of hot flushes increased from 10% during the premenopausal period to about 50% just after cessation of menses.
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Influenza Vaccination and Reduction in Hospitalizations; Screening Men
for Prostate and Colorectal Cancer; Weight Loss in CHF and Treatment
with ACE-I; Impaired Fasting Glucose vs Impaired Glucose Tolerance;
Risk Stratification in Long-QT Syndrome; EBCT, Motivation, Behavioral
Change, and Cardiovascular Risk Profile
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This review will provide an overview of SARS for the primary care physician, including epidemiology, etiology, review of the clinical and laboratory features as well as diagnosis, therapy, and prevention of SARS.
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The Women's Health Initiatives was halted a year ago, but fallout
from this landmark study continues. The study was designed to identify
the risks or benefits of estrogen plus progesterone vs placebo in
healthy postmenopausal women.
