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Magnesium sulfate is more effective than nimodipine for prophylaxis against seizures in women with severe preeclampsia.
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Only tamoxifen has enough evidence to recommend it for the prevention of breast cancer, and its use is limited to very high-risk women with a low risk of side effects.
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Postmenopausal estrogen-progestin therapy increased the risk of breast cancer in a population-based cohort in Sweden, and estrogen-only did not.
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Warfarin Effectively Prevents Venous Thromboembolism; Vitamin D Reduces Osteoporotic Fractures; Adefovir Effective for Hepatitis B Treatment; Ibuprofen/Aspirin Study Revisited; ACE Inhibitors Favored in Cardiovascular Care; Digoxin Dosing and Heart Failure
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Bacterial contamination of bronchoscopes, resulting in both unnecessary antibiotic use and clinical infection, resulted from a change in design of the instruments.
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Twenty-nine percent of patients newly identified as carrying MRSA will have subsequent MRSA infection over the following 18 months.
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Updates
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Tenofovir effectively reduces HBV replication over 24 weeks of therapy in HIV-coinfected patients.
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The French use antibiotics quite differently from the Germans, for a variety of reasons, including cultural factors and regulations, in addition to physician habits and patient expectations.
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Metronidazole, piperacillin/tazobactam, and the carbapenems remain the most reliably active against B fragilis group organisms.