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  • Clinical Briefs

    Effect of Ibuprofen on Cardioprotective Effect of Aspirin; Relapse Prevention with Antidepressant Drug Treatment in Depressive Disorders; Incidence and Preventability of Adverse Drug Events Among Older Persons in the Ambulatory Setting
  • Nonsteroidal Antiinflammatory Drugs as a Risk Factor for Acute Diarrhea: A Case Crossover Study

    Recent NSAID use is a risk factor for acute diarrhea, a consideration for general physicians along with GI specialists.
  • Drug Treatments to Prevent Breast Cancer

    Only tamoxifen has enough evidence to be recommend for the prevention of breast cancer, and its use is limited to very high-risk women with a low risk of side effects.
  • Diabetic Neuropathy

    This study shows that intravenous amantadine is beneficial in reducing the pain of painful peripheral neuropathy, with an effect sustained for at least 1 week after an infusion.
  • Pharmacology Update: Azelaic Acid Gel 15% (Finacea — Berlex)

    Azelaic acid gel has been approved for the treatment of mild-to-moderate rosacea. This naturally occurring saturated dicarboxylic acid is formulated in an aqueous gel formation for this indication.
  • ECG Review: What Might the Echo Show?

    The ECG in the Figure was obtained from a 55-year-old man with a history of heart failure and emphysema. What might his echocardiogram show?
  • Pharmacology Watch: Warfarin Effectively Prevents Venous Thromboembolism

    Warfarin Effectively Prevents Venous Thromboembolism; Vitamin D Reduces Osteoporotic Fractures; Adefovir Effective for Hepatitis B Treatment; Ibuprofen/Aspirin Study Revisited; ACE Inhibitors Favored in Cardiovascular Care; Digoxin Dosing and Heart Failure
  • Clinical Briefs in Primary Care

    Use of Hip Protectors in Nursing Homes; Disclosing Unanticipated Outcomes and Medical Errors; Non-Invasive Positive Pressure Ventilation to Treat Respiratory Failure Resulting from Exacerbations of COPD; Effect of Ibuprofen on Cardioprotective Effect of Aspirin; Antidepressant Drug Treatment in Depressive Disorders; Adverse Drug Events Among the Elderly in the Ambulatory Setting
  • More Help with Sepsis from Biologics

    rhIL-11 given orally to neutropenic rats experimentally infected with Pseudomonas aeruginosa appears to preserve the integrity of gut epithelia while resulting in fewer pathologic changes, lower levels of endotoxin and numbers of bacteria in the tissues, and longer survival. Recombinant human interleukin 11 (rhIL-11) administration was associated with a reduction in a variety of infectious complications, including bacterium due to Gram-negative bacilli originating from the gut among patients given intensive chemotherapy for hematologic malignancies.
  • Tips on TIPS Infections

    Infection of transjugular intrahepatic shunt devices is caused by a variety of bacteria, mostly of gastrointestinal origin. Inability to remove the device without hepatic transplantation makes management of the infection difficult.