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Citizen Science Projects Surging, But Often Lack IRB Ethical Oversight

Failure to return results, exploitation of participants, poor quality data, and power imbalance are top ethical worries. Citizen scientists should pay attention to issues of power and exploitation, and think about what processes to use to stay ahead of those concerns.

Clindamycin Vaginal Gel 2% (Xaciato)

Clindamycin gel can be prescribed to treat bacterial vaginosis in women age 12 years and older.

Screen Older Heart Failure Patients for Transthyretin Cardiac Amyloidosis

A screening study of heart failure patients ≥ age 60 years, left ventricular ejection fraction ≥ 40%, and left ventricle wall thickness ≥ 12 mm revealed 6.3% prevalence of transthyretin cardiac amyloidosis, a highly treatable disease.

Is Physical Activity Associated with Mortality Risk in Parkinson’s Disease?

In individuals with Parkinson’s disease (PD), physical activity (PA) at all intensities was associated with lower all-cause mortality rates, with the greatest reduction seen in individuals who maintained PA before and after PD diagnosis.

Multiple Sclerosis and Immune Response to COVID-19 Vaccination

A large group of patients with multiple sclerosis taking various disease-modifying therapies did not respond uniformly to COVID-19 vaccination.

USPSTF Weighs in on Key Cardiology Topics

Should clinicians screen asymptomatic older patients for atrial fibrillation? What is the best treatment course for patients without cardiovascular disease risk?

Cancer Moonshot, Redux

President Biden recommits to ambitious project that started when he was vice president.

Is Cannabis Use a Marker for Atherosclerotic Cardiovascular Disease?

Admitted cannabis use was associated with an increase in the pooled risk of atherosclerosis score in a graded fashion based on the frequency of use, which was consistent across subgroups based on the presence of hypertension, obesity, and hyperlipidemia.

How Certain is a Negative Echocardiogram for Excluding Infective Endocarditis?

Applying the proposed strict negative criteria for infective endocarditis (IE) on the first echocardiogram indicated this approach largely prevented unnecessary repeat tests unless clinically indicated for continued suspicion of IE.

Does Electrode Position Affect the Results of Cardioversion?

A randomized trial of anteroposterior vs. anterolateral electrode positioning for the biphasic energy cardioversion of atrial fibrillation showed the anterolateral positioning is most effective.