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The optimal timing of surgery for asymptomatic severe mitral valve regurgitation (MR) is unclear. Thus, Kang et al from South Korea studied the outcomes of patients treated with early surgery to those treated more conservatively in a prospective observational study.
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Dronedarone is a new antiarrhythmic drug with structural similarities to amiodarone.
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The clinical utility of microvolt T-wave alternans (MWTA) testing to detect subtle beat-to-beat oscillations in the electrocardiogram's T-wave amplitude as a non-invasive method for predicting sudden cardiac death remains undetermined.
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Individualization of therapy with pharmacogenetics; the rate vs rhythm debate; the FDA's Risk Evaluation and Mitigation Strategy; FDA actions.
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Small studies with older equipment at single centers have shown that coronary CT angiography (CTA) is promising for evaluating coronary anatomy. New 64-slice CT scanners have improved spatial and temporal resolution. Thus, these investigators from the Netherlands conducted a prospective, multi-centered, multi-vendor study to assess the accuracy of 64-slice CTA for in dentifying significant coronary artery disease (CAD) in symptomatic patients undergoing conventional coronary angiography (CCA).
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In this paper, stevenson et al, from 18 centers with expertise in ventricular tachycardia (VT) ablation, report the results of VT ablation using the Thermo°Cool-irrigated, tipped-radiofrequency ablation catheter. Patients were eligible for the study if they had multiple episodes of sustained monomorphic VT that had required either cardioversion or antiarrhythmic drug administration in the previous six months.
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FDA warning on topical anesthetics; antipsychotics increase sudden cardiac death; the step up vs step down debate; treating pain, fatigue, mood, and sleep in fibromyalgia; FDA Actions.
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The goal of treatment during ST elevation myocardial infarction (STEMI) is early reperfusion of the occluded coronary artery, as this has been shown to reduce mortality and morbidity.