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Ischemic mitral regurgitation (IMR) in patients referred for coronary artery bypass graft surgery (CABG) improves with revascularization in some cases, but in other cases it does not.
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The timing of mitral valve surgery in patients with severe organic mitral regurgitation (MR), but without symptoms, is controversial.
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Current indications for cardiac-resynchronization therapy (CRT) require that patients have New York Heart Association (NYHA) Class III or Class IV heart-failure symptoms. However, long-standing ventricular dyssynchrony can lead to left-ventricular remodeling and decreased left-ventricular ejection fraction.
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Dabigatran etexilate is an oral compound that is converted after absorption by a serum esterase to dabigatran, a direct competitive inhibitor of thrombin.
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Erratic intraindividual INR values on chronic warfarin therapy are thought to be due to variability in vitamin K intake in the diet. Thus, de Assis et al from Brazil hypothesized that a dietary, vitamin K management strategy would result in improved long-term anticoagulation as compared to traditional systems based upon drug-dose adjustments alone.
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Depression and pregnancy, new vaccine recommendations from the CDC, cortico-steroids and/or antivirals for Bell's palsy, rasagiline and Parkinson's disease, and FDA Actions.
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Many clinical trials have confirmed the benefit of early invasive therapy for high-risk patients presenting with acute coronary syndromes (ACS). However, the optimal timing of cardiac catheterization in this group remains unknown.
