Clinical Cardiology
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Late-breaking Clinical Trials from the Heart Rhythm Society May 2017 Scientific Sessions
Late-breaking findings of several important clinical trials were presented at this year’s Heart Rhythm Society Scientific Sessions in Chicago. A selection particularly relevant to the general cardiology community is presented here.
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Value of Monitoring ECG Lead aVR in Exercise Stress Testing
Analysis of ST transients in aVR during exercise ECG testing can provide additional diagnostic information in patients suspected of having ischemic heart disease.
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ECG Criteria for Left Ventricular Hypertrophy Revisited
In comparison to other popular criteria for the ECG diagnosis of left ventricular hypertrophy, the newly proposed Peguero-Lo Presti criteria, when tested in patients with proximate ECGs and echocardiograms, showed superior sensitivity and accuracy.
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Primary Aldosteronism in Hypertensive Patients
Primary aldosteronism was discovered in 6% of hypertensive patients in a group of primary care practices in Italy, and these patients exhibited more target organ damage.
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Remote Hemodynamic Monitoring for Heart Failure Effective in ‘Real-world’ Setting
In a retrospective study of Medicare claims data, use of the CardioMEMS implantable pulmonary artery pressure sensor was associated with reductions in both heart failure hospitalizations and comprehensive heart failure costs.
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What Cardiologists Need to Know About Instantaneous Wave-free Ratio
Two trials defined instantaneous wave-free ratio as the new standard for physiologic lesion assessment in the cardiac cath lab.
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Tolvaptan Fails to Improve Dyspnea in Acute Heart Failure
In patients hospitalized for acute heart failure, adding tolvaptan to furosemide lead to increased weight and fluid loss, but did not improve dyspnea at 24 hours.
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Can Echo/Doppler Accurately Estimate LVEDP in Pulmonary Hypertension Patients?
In patients with pulmonary hypertension evaluated in a specialty clinic, echo/Doppler estimation of left ventricular end-diastolic pressure is not reliable for the determination of pre- vs. post-capillary pulmonary hypertension.
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Cardiac Resynchronization Therapy Reduces New Onset Ventricular Arrhythmias
In an analysis of the landmark Resynchronization in Ambulatory Heart Failure Trial, patients without prior ventricular arrhythmias randomized to cardiac resynchronization therapy experienced significantly less new onset ventricular arrhythmias than those randomized to implantable cardioverter defibrillator alone.
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Predicting Electrical Cardioversion Failure
A study of the 30-day success rate of electrical cardioversion of acute atrial fibrillation revealed five clinical predictors of recurrence.