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More than 200,000 Riata family implantable cardioverter-defibrillator (ICD) leads from St. Jude Medical were implanted worldwide. Recently, the FDA issued a Class I recall on this lead because of the appearance of defects in the lead insulation that may lead to externalization of the conductor wires.
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This paper reports registry data from a large, single-center patient cohort with myotonic dystrophy type 1 (DM1). Between January 2000 and December 2009, 914 adult patients were included in the DM1 Heart Registry at the authors' institution.
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Aspirin and cancer prevention; rivaroxaban for pulmonary embolism; new rhinosinusitis practice guidelines; and FDA actions.
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The Randomized Evaluation of Long-Term Anticoagulation Therapy (RE-LY) Study compared two doses of dabigatran, a direct thrombin inhibitor, with warfarin for the prevention of stroke and systemic emboli in patients with nonvalvular atrial fibrillation (AF).
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Some patients who experience stroke or transient ischemic attack (TIA) of unknown cause (i.e., cryptogenic) are subsequently found to have a patent foramen ovale (PFO).
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Patients presenting to the emergency department (ED) with chest pain are often admitted to "rule out" myocardial infarction (MI). Many of the patients are subsequently found to have noncardiac causes of chest pain.
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In the setting of acute ST segment elevation myocardial infarction (STEMI), warfarin is indicated for atrial fibrillation, a large dyskinetic or aneurysmal area of the left ventricle, or mural thrombus.
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Angiotensin-converting enzyme inhibitor (ACEI) therapy may be beneficial during coronary artery bypass graft (CABG) surgery because of its anti-inflammatory and other vascular benefits.
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Various risk schemes have been promulgated for assessing the risk of stroke and bleeding in patients with atrial fibrillation (AF). These investigators used the Swedish Atrial Fibrillation cohort study to investigate the comparative utility of four schemes that have been validated in AF cohorts: CHADS2, CHA2DS2-VASc, HAS-BLED, and HEMORR2HAGES.
