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In older adults, no association was found between subclinical hypothyroidism and coronary heart disease, heart failure, and cardiovascular mortality.
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Medications for Risk Reduction of Breast Cancer in Women
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In men 20-50 years of age, testosterone deficiency accounted for decreases in lean muscle mass, size, and strength while estrogen deficiency primarily accounted for increases in body fat, and both contributed to the decline in sexual function.
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There is a known association of obesity and glucose intolerance with pancreatic cancer but whether this is due to the effect of high glucose itself, insulin resistance, or pancreatic ß-cell dysfunction is unknown.
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An irreversible epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor (TKI) has been approved for first-line treatment of non-small cell lung cancer (NSCLC) with certain EGFR mutations.
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High-sensitivity cardiac troponin (hs-cTn) assays have higher sensitivity for myocardial ischemic injury and necrosis than conventional assays, but with reduced specificity.
An hs-cTn level below the detectable limit is very accurate at excluding AMI in an ED patient with chest pain.
The precision of hs-cTn assays enables serial sampling of cardiac biomarkers to exclude AMI to be done over 1-2 hours as opposed to 3-9 hours for conventional cTn assays.
A normal coronary CT angiography (CCTA) (< 50% stenosis in any epicardial coronary artery) performed in an ED patient with chest pain is associated with a good 30-day outcome.
Use of CCTA in ED patients with chest pain is associated with reduced length of stay, admissions, and overall costs compared to typical care that often involves myocardial perfusion imaging.
CCTA is associated with a small but consistent increase in invasive coronary angiograms and reperfusion procedures compared to typical care that often involved myocardial perfusion imaging.
