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In this in-depth examination of 111 patients at a center in the original ARDS Net low-tidal-volume study, patients managed with 6 mL/kg or less did not require more sedation during the first 48 hours than those managed with tidal volumes of 12 mL/kg.
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This 3-year cohort surveillance study of all adult patients admitted to ICUs in one region found that they were common (developing in 6.5% of patients, or 9.6 UTIs per 1000 ICU days) but did not contribute independently to mortality.
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This single center observational cohort study reveals that ARDS survivors have persistent neurocognitive, psychiatric and quality of life impairments at 2 years.
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Given the importance of acute bacterial rhinosinusitis (ABRS), a commonly encountered outpatient infection, this article attempts to outline in evidence-based detail what the authors conclude to be optimal, risk-stratified, empiric treatment recommendations. In addition, this review identifies key clinical findings, resistance patterns, risk factors, coexisting conditions, and other clinical triggers supporting referral of patients with ABRS to an otolaryngologist for more invasive i.e., multimodal surgical and more intensive antimicrobial management strategies.
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Use of risedronate in women 80 years and older reduced the incidence of vertebral fractures and was well tolerated.
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Maintaining INRs (International normalized ratios) between 2 and 3 is safer than INRs below 2, as suggested by some guidelines.
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Most neoplastic lesions are not detected either by Hemoccult screening or by multitarget analysis of fecal DNA. Nevertheless, the fecal DNA analysis was significantly more efficient than Hemoccult testing.