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The combination of ampicillin and ceftriaxone was effective in treatment of endocarditis due to E. faecalis. Efficacy was similar for infections involving isolates with and without high-level aminoglycoside resistance.
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In this study of 310,311 veterans aged 65 or older who underwent major noncardiac surgical procedures, 30-day mortality increased 1.6% for every percentage-point decrease in preoperative hematocrit below 39%.
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Methylation of 16S ribosomal RNA (rRNA) has emerged as an important mechanism of resistance to aminoglycosides in pathogens including Enterobacteriaceae and non-fermenters including Pseudomonas aeruginosa and Acinetobacter species.
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In this paper, Hart and colleagues report the results of a meta-analysis of antithrombotic therapy in patients with nonvalvular atrial fibrillation (NVAF).
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Aliskiren is a new class of drugs that directly inhibit renin and is approved in the U.S.A. for the treatment of hypertension. Valsartan is the best selling antihypertensive medication in the world.
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This report describes a large group of patients with hypertrophic cardiomyopathy (HCM) who underwent implantable cardioverter defibrillator (ICD) implantation at 42 referral and nonreferral institutions in the United States, Europe and Australia.
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Dalal and his colleagues describe data from the Johns Hopkins Arrhythmogenic Right Ventricular Dysplasia/Cardiomyopathy (ARVD/C) registry concerning the efficacy of catheter ablation for ventricular tachycardia (VT) in this condition.
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The increasing use of 64-slice computed tomography or MSCT is beginning to significantly impact the medical literature.
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Patients with peripheral artery disease are at high risk for cardiovascular complications. Antiplatelet drugs are routinely prescribed for these patients, but is adding an oral anticoagulant of value?