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The catheter ablation versus antiarrhythmic Drugs for Atrial Fibrillation (A4) study compared radio-frequency catheter ablation to antiarrhythmic therapy in selected patients with paroxysmal atrial fibrillation (PAF).
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Drug combinations for hypertension; tenecteplase for out-of-hospital cardiac arrest; CAM most commonly used for back, neck, and arthritis pain; FDA Actions.
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Results of the SELECT trial, a large randomized, placebo-controlled, double-blind trial designed to help determine whether selenium, vitamin E, or both could safely prevent prostate cancer in middle-aged and older men, were not to be published for another four years. Interim analyses, however, revealed no benefit from therapy, and even some potential health concerns.
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This article was a systematic review and meta-analysis of high-quality randomized controlled trials determining the effect of fiber, antispasmodics, and peppermint oil in the treatment of irritable bowel syndrome, and demonstrating superiority of the three examined therapeutic modalities as compared to placebo.
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Margarines containing plant sterols and stanols can be an effective long-term therapeutic intervention to aid with cholesterol lowering in people already on a stable statin regimen.
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Osteoarthritis is the most common form of arthritis and a leading cause of disability in the United States.
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Carnitine supplementation produced beneficial changes in endothelial function as measured by flow-mediated dilation (FMD) after a high-fat meal. No significant differences were found for other biomarkers of inflammation and oxidative stress.
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A well-regarded, standardized extract of Ginkgo biloba does not appear to help prevent development of dementia in seniors with baseline normal or mildly impaired cognitive function. Whether use of ginkgo earlier in life has a primary preventive effect on development of dementia remains to be determined.
