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This meta-analysis of 12 clinical trials in adult patients with acute respiratory failure showed that extubation directly to non-invasive ventilation before weaning would normally have been attempted decreases mortality, ventilator-associated pneumonia, and length of stay especially for patients with COPD.
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Patients who receive proton-pump inhibitors in the hospital are at increased risk for hospital-acquired pneumonia.
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This paper describes the results of an epidemiologic survey of the results of in-hospital cardiopulmonary resuscitation (CPR) in U.S. hospitals.
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Although still controversial, pooling of data from randomized trials suggests the neuroprotective benefit of magnesium sulfate in patients in preterm labor prior to 34 weeks of gestation.
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Based upon an increased incidence of heart failure with alpha 1-adrenergic antagonists treatment of hypertension, there has been concern about using alpha blockers for benign prostatic hypertrophy (BPH) in patients with heart failure, yet these drugs are highly efficacious for this common condition.
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Pulmonary arterial hypertension (PAH) is a dreaded multifactorial disease that is usually fatal. PAH can be a result of a number of conditions, including chronic thromboembolic hypertension, HIV, and congenital cardiac lessons, such as a large ASD with pulmonary shunting resulting in decreased nitric oxide (NO) expression.
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Functional mitral regurgitation (FMR), occurring in heart failure, portends an adverse prognosis.
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This report from the Framingham heart study looks at the prognostic significance of PR interval prolongation in ambulatory, relatively healthy individuals.
