Early goal-directed therapy (EGDT) has been shown to reduce hospital mortality from severe sepsis and septic shock. Puskarich et al hypothesized that long-term outcome would also be improved.
In this issue: Statin and niacin increase HDL-C, omeprazole reduces effectiveness of clopidogrel, darbe-poetin increases risk of stroke, statins decrease risk of gallstone disease, FDA Actions.
Prone positioning has been advocated as a management strategy for patients with acute respiratory distress syndrome (ARDS), but despite evidence of improved oxygenation with the technique, numerous studies have yet to establish a mortality benefit from the practice.
Prior studies have demonstrated that delayed transfer of critically ill patients from the emergency department (ED) to the ICU (> 6 hours) prolongs ICU and hospital stay.
Every intensivist recognizes that families play a prominent role in ICU decision making.
