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Does Gluten Cause Health Problems in Patients Without Celiac Disease?

Gluten is a protein complex that may be inflammatory to humans and is increasingly recognized as a possible cause of numerous health problems such as irritable bowel syndrome, fibromyalgia, skin conditions, allergies, autoimmune arthritis, and neurodegenerative conditions.

Does Beef Get a Bad Rap?

Contrary to prevailing opinion, eating lean beef may not be bad and perhaps might even favorably affect systolic blood pressure and vascular constriction.

Clinical Briefs

Should the Physician Go Where the Sun Does Not?

In a meta-analysis of multiple prospective cohort studies, the lowest vitamin D metabolite (25-hydroxyvitamin D) quintile was associated with increased all-cause mortality, cardiovascular mortality, and cancer mortality.

Human Insulin Inhalation Powder (Afrezza®)

A second inhalation rapid human insulin has been approved by the FDA. The first inhaled insulin (Exubera) was approved in 2006 and was withdrawn from the market by Pfizer due to low acceptance and poor sales after about 13 months on the market

Emergency Medicine Reports - Full November 16, 2014 Issue in PDF

Rheumatoid Arthritis: An Emergency Physician’s Perspective

Rheumatoid arthritis (RA) is a systemic polyarticular form of inflammatory arthritis of unclear etiology. It primarily involves the synovial joints and is commonly symmetric. Joint pain and swelling are most commonly seen in patients with this condition. The presence of autoantibodies such as rheumatoid factor (RF) and anti-citrullinated protein antibodies (ACPAs), which the anti-cyclic citrullinated peptide (CCP) falls under, are found in the majority of patients. Left untreated, there is a high risk of significant deformity and disability.

Medical Treatment Is Effective, But Only if It is Used

In this randomized controlled trial, those sleep apnea patients who received a brief (< 1 hour, total) motivational education program had substantially better continuous positive airway pressure adherence in a short-term follow-up.

Who Is Shopping for You?

In a study of young adults, attempted physician deception to obtain a pharmaceutical drug was found to exist in a limited manner along with general characteristics of those patients who may divert medications.

Ledipasvir and Sofosbuvir Tablets (Harvoni ® )

The first fixed-dose combination drug product has been approved for the treatment of chronic hepatitis C virus (HCV) genotype 1 infection. The combination contains a previously approved HCV nucleotide analog NS5B polymerase inhibitor, sofosbuvir (SOF), and a NS5A inhibitor, ledipasvir (LDV). This represents the first treatment option for HCV genotype 1 that does not require ribavirin or interferon.