Current American College of Cardiology/ American Heart Association (ACC/AHA) Guidelines recommend withholding non-steroidal anti-inflammatory drugs (NSAIDs) from patients who have suffered a myocardial infarction (MI) and substitution of another analgesic such as acetaminophen. If NSAID therapy is unavoidable, the guidelines recommend the shortest duration possible.
This single-center, double-blind, randomized, controlled crossover trial demonstrated that administration of 100% oxygen to stable patients with obesity hypoventilation syndrome leads to decreased minute ventilation, increasing dead-space to tidal volume ratio, and worsening hypercapnia.
