Clinical Cardiology Alert – May 1, 2022
May 1, 2022
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Comparison of Treatments Highlights Poor Outcomes for TAVR Patients with Infective Endocarditis
In this analysis of a large registry of transcatheter aortic valve replacement patients with confirmed endocarditis, most were treated with antibiotics without surgery. In-hospital and one-year mortality rates were high and were not much better in patients who underwent surgery.
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Thrombolysis vs. Surgery for Thrombosed Mechanical Prosthetic Valves
A study of patients with obstructive prosthetic valve thrombosis that deployed low-dose, slow infusion thrombolysis or surgery using shared decision-making, showed thrombolysis was highly effective and resulted in fewer major complications than surgery.
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Comparing CT Angiography to Invasive Angiography for Stable Chest Pain Patients
A trial of initial coronary CT angiography vs. invasive angiography revealed outcomes over a median 3.5-year follow-up were similar, but procedure-related complications were more common in the invasive group.
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Detecting Cancer Treatment-Related Cardiac Dysfunction
When searching for breast cancer-related cardiac dysfunction, a sequential algorithm using echo ejection fraction and strain parameters produced an area under the receiver operating curve of 89%. Adding biomarkers did not improve the ability to diagnose cardiac dysfunction.
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Regarding Exercise Capacity Past Age 75 Years, What Is Normal?
A group of researchers delivered results that could help inform clinicians about the expected exercise test performance of older patients.