Clinical Cardiology Alert – November 1, 2017
November 1, 2017
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Late-breaking Clinical Trials From the European Society of Cardiology Congress, August 2017
Recent findings of several important clinical trials in atrial fibrillation management were presented as part of the “Hot Line” sessions at this year’s European Society of Cardiology Congress in Barcelona, Spain. A selection particularly relevant to the general cardiology community is presented here.
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Patent Foramen Ovale Intervention Rises to Occasion in Cryptogenic Stroke
After years of uncertainty, three large randomized trials have shown a benefit to patent foramen ovale closure in reducing recurrence after cryptogenic stroke in the right patients.
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Can Medical Therapy Improve Functional Mitral Regurgitation?
Among patients who presented with heart failure with reduced ejection fraction and severe functional mitral regurgitation, mitral regurgitation improved in 38% of patients with medical management. Improvement in mitral regurgitation was associated with increased survival.
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Transcatheter Mitral Valve Replacement as an Alternative to Other Surgical Options
A large registry study of transcatheter mitral valve replacement (TMVR) in patients with degenerated mitral valve bioprostheses or failed mitral annuloplasty repairs who were at high risk for repeat surgery showed that TMVR can be performed successfully. However, the initial and long-term results are better in the degenerated bioprothesis group.