Clinical Cardiology Alert – April 1, 2016
April 1, 2016
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Outcome of PCSK9 Inhibitor-treated Patients
In a recent study, proprotein convertase subtilisin-kexin type 9 serine protease inhibitors significantly improve lipid profiles and reduce all-cause mortality, but were associated with more neurocognitive adverse events than placebo.
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TAVR Still a Viable Option for Many Left Main Disease Patients
Performing planned left main percutaneous intervention before or during transcatheter aortic valve replacement does not confer increased risk of short- or intermediate-term adverse outcomes.
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Prognostic Value of Coronary Calcium on Standard Chest CT Scans
Coronary calcium scan on standard CT scans performed for other indications is of equivalent prognostic value to that seen on ECG-gated coronary studies and should be included in radiology test reports.
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Cardiopulmonary Exercise Testing and Survival in Systolic Heart Failure
A large study of patients with chronic systolic heart failure undergoing cardiopulmonary exercise testing found peak oxygen uptake, exercise duration, and percent predicted peak oxygen uptake were the strongest predictors of survival.
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Ventricular Tachycardia Ablation for Recurrent Arrhythmia and Coronary Artery Disease
Acute and long-term success rates with ventricular tachycardia ablation in patients with coronary artery disease are relatively high with an acceptably low complication rate.
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The Current Outlook for Cardiac Tamponade
In the modern era, cardiac tamponade is most commonly caused by malignancies with poor prognosis. As compared to older literature, iatrogenic causes have increased, most resulting from complications of percutaneous coronary intervention.