Clinical Cardiology Alert – December 1, 2015
December 1, 2015
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Optimal Beta-blocker Dose Post-MI
ABSTRACT & COMMENTARY: A look at survival rates using high and low doses of beta blockers.
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Aortic Valve Replacement in Asymptomatic Patients: Can Registry Data Replace Randomized, Controlled Trials?
Patients with severe asymptomatic aortic stenosis managed conservatively have “dismal” outcomes in real-world practice.
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Temporal Relationship Between Atrial Fibrillation and Ischemic Stroke?
Multiple hours of atrial fibrillation had a strong but transient effect raising stroke risk, suggesting that a strategy of intermittent targeted usage of rapidly acting anticoagulants might merit further consideration by a randomized trial.
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Utility of Non-traditional Risk Factors
Adding additional risk factors not in the pooled risk equation to low-risk subjects identified a sub-group with an observed event rate > 7.5% who may warrant statin therapy.
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Left Ventricular Assist Devices for Ambulatory Heart Failure: Weighing the Risks and Benefits
Recent data support the use of the HeartMate II left ventricular assist devices in functionally limited, non-inotrope-dependent heart failure patients who have poor quality of life and meet FDA criteria for destination therapy LVAD.