Clinical Cardiology Alert – January 1, 2004
January 1, 2004
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ApoA-1 Milano: What’s the Fuss?
This widely publicized small trial has catapulted the mutant form of ApoA-1 Milano into the limelight. Many investigators have been working with this interesting lipoprotein since it was discovered in the 1980s that 38 carriers from a small village in Northern Italy have very low HDL levels but very little vascular disease. -
Catheter Ablation for Paroxysmal Atrial Fibrillation
In this paper, Oral and colleagues compared 2 current ablation techniques in patients with paroxysmal atrial fibrillation. -
Prophylactic Catheter Ablation in Asymptomatic WPW Patients
In this paper from 2 Italian centers, Pappone and colleagues report the results of a randomized trial of prophylactic catheter ablation in previously asymptomatic patients with Wolff-Parkinson-White syndrome. -
Normal Thickness Pericardial Constriction
Talreja and colleagues from the Mayo Clinic in Rochester, Minn, reviewed biopsy specimens and clinical features of 143 patients who had pericardiectomy for proven pericardial constriction. -
Acute Anterior Myocardial Infarction with Inferior ST Elevation
In patients with acute anterior myocardial infarction the significance of inferior ECG ST-segment elevation is unclear. Thus, investigators from the GUSTO-I angiographic and the GUSTO-IIb angioplasty substudies evaluated the 1046 patients with anterior ST elevation and divided them into 3 groups. -
Inheritance of Sudden Arrhythmic Death Syndrome
A United Kingdom survey of sudden arrhythmic death syndrome in 32 victims aged 4-64 with normal hearts at autopsy and a negative toxicologic screening test evaluated first-degree relatives of these victims. -
Beta-Blockers and Dipyridamole Sestamibi Studies
Although beta-blockers are known to reduce the sensitivity of exercise and dobutamine sestamibi SPECT imaging for the detection of coronary artery disease, little is known about their effects on vasodilator stress scintigraphy. Thus, Taillefer and colleagues studied 21 patients with catheter proven coronary artery disease during 3 different treatments on different days assigned in a random fashion. -
Pharmacology Watch: Vioxx Might Control Postoperative Knee Pain
Oral rofecoxib (Vioxx) may have a role in controlling postoperative pain patients undergoing knee surgery. -
Clinical Briefs in Primary Care Supplement