Clinical Cardiology Alert – September 1, 2009
September 1, 2009
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Sirolimus-Eluting Stents vs. MIDCAB for Isolated Proximal LAD Disease
The debate continues as to whether coronary artery bypass graft (CABG) surgery with left-internal mammary artery (LIMA) or stenting is the best treatment for proximal left-anterior descending coronary artery (LAD) lesions. -
Alpha Blockers and Heart Failure
Based upon an increased incidence of heart failure with alpha 1-adrenergic antagonists treatment of hypertension, there has been concern about using alpha blockers for benign prostatic hypertrophy (BPH) in patients with heart failure, yet these drugs are highly efficacious for this common condition. -
Tadalafil for Pulmonary Arterial Hypertension
Pulmonary arterial hypertension (PAH) is a dreaded multifactorial disease that is usually fatal. PAH can be a result of a number of conditions, including chronic thromboembolic hypertension, HIV, and congenital cardiac lessons, such as a large ASD with pulmonary shunting resulting in decreased nitric oxide (NO) expression. -
Unexplained Cardiac Arrest Evaluation
In this paper, Krahn et al from a Canadian consortium report on the results of systematic evaluations in patients with unexplained cardiac arrest due to ventricular tachycardia or ventricular fibrillation. -
Percutaneous Mitral Annuloplasty for Functional Mitral Regurgitation in Heart Failure
Functional mitral regurgitation (FMR), occurring in heart failure, portends an adverse prognosis. -
Prognostic Value of a Prolonged PR Interval
This report from the Framingham heart study looks at the prognostic significance of PR interval prolongation in ambulatory, relatively healthy individuals. -
Clinical Briefs in Primary Care Supplement
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Pharmacology Watch
Tamoxifen and CYP2D6 inhibitors, FDA Actions, and FDA Warnings.