Clinical Cardiology Alert – April 1, 2013
April 1, 2013
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Left Atrial Appendage Occlusion vs Warfarin for Nonvalvular AF
A trial fibrillation (AF) is a major source of morbidity in patients and cost to the health care community. In the presence of risk factors for thromboembolism, AF is associated with an increased risk of stroke, and this risk is reduced with warfarin. -
Tight vs Loose Rate Control in Permanent Atrial Fibrillation
The Rate Control Efficacy in Permanent Atrial Fibrillation (RACE II) trial compared strict rate control vs lenient rate control in patients with permanent atrial fibrillation. In this substudy, the RACE II investigators report results based on three groups of patients: those with successful strict rate control, those with unsuccessful rate control, and those with lenient rate control. -
Does Therapeutic Hypothermia Cause Stent Thrombosis?
Therapeutic hypothermia (THT) in survivors of cardiac arrest due to shockable rhythm is associated with improved neurological outcomes. -
Hemorrhagic Stoke with Dual Antiplatelet Therapy
The REduction of Atherothrombosis for Continued Health (REACH) study is an international registry of patients on antithrombic therapy that provides an opportunity to evaluate the risk of ischemic and bleeding outcomes in patients with coronary artery disease (CAD). -
Prosthetic Valve Thrombosis
The use of thrombolysis for prosthetic valve thrombosis (PVT) is controversial and various guidelines rate it differently. However, since PVT carries a significant mortality risk, more information on proposed therapies would be valuable. -
Can Cardiac Resynchronization Therapy Use be Expanded?
The Evaluation of Resynchronization Therapy for Heart Failure (LESSER-EARTH) trial tested the hypothesis that cardiac resynchronization therapy in addition to optimal medical therapy would benefit patients with severe congestive heart failure but no pacing indication and a QRS duration < 120 milliseconds (msec). -
Pharmacology Watch: Is This the End of the Road for Calcium Supplementation?
Calcium supplementation in women; type 2 diabetes treatments and pancreatitis risk; treating chronic idiopathic urticaria; rivaroxaban and VTE; and FDA actions. -
Clinical Briefs in Primary Care Supplement