Clinical Cardiology Alert – January 1, 2005
January 1, 2005
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Prophylactic Use of An ICD After Acute Myocardial Infarction
The Defibrillator in Acute Myocardial Infarction Trial examined the question whether prophylactic implantable cardioverter defibrillator (ICD) therapy begun soon after myocardial infarction would reduce long-term mortality. -
Antiplatelet or Anticoagulant Therapy in Atrial Fibrillation
The addition of antiplatelet therapy to reduced intensity anticoagulation in atrial fibrillation patients reduces death and embolic events without increasing bleeding. -
Coronary Revascularization Before Vascular Surgery
The substantial differences in opinion concerning the need for revascularization prior to elective vascular surgery are present among cardiologists. -
Statin Metabolism Interactions
Pravastatin is the statin with the least interactions with cytochrome P450-(CYP) 3A4 inhibitors. -
Nifedipine For Chronic Stable Angina
The addition of nifedipine to conventional treatment in patients with chronic stable angina did not affect overall event-free survival, but was safe and reduced the need for coronary interventions. -
Atenolol For Hypertension
Atenolol is unsuitable as a first-line drug in hypertension. -
Pharmacology Watch: Hypertension: Therapy vs Calcium Channel Antagonists
Pharmacotherapy of hypertension has been much in the news in the last 2 months. Standard therapies such as atenolol have been challenged, while calcium channel antagonists may be making a comeback. -
Clinical Briefs in Primary Care Supplement