Clinical Briefs in Primary Care – December 1, 2015
December 1, 2015
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Leaving the Annual Physical Behind
To date, the annual physical has shown minimal, if any, benefit and potential for harm.
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Is Breakfast the Most Important Meal of the Day?
Omission of breakfast was associated with less secretion of insulin and glucagon-like peptide and higher levels of free fatty acids, glucose, and glucagon.
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Confirming the Value of Total Knee Replacement
Total knee replacement provides better outcomes for pain, symptoms, activities of daily living, and quality of life than medical therapy alone.
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Manipulating the Microbiome to Enhance Metabolic Functions
The recognition that incretin secretion is impaired in type 2 diabetes stimulates consideration of a similar trial in diabetic patients.
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No Payoff to Physical Therapy After Healed Ankle Fracture
After successful healing of an ankle fracture, a program of supervised physical therapy does not appear to improve outcomes.
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Bisphosphonates May Impact Bone Recurrence in Postmenopausal Women with Breast Cancer
Although the rate of distant recurrence and breast cancer mortality were statistically and significantly superior in women who had been treated with bisphosphonates, the absolute degree of benefit was of dubious clinical relevance.