AIDS Alert Archives – January 1, 2005
January 1, 2005
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New research data show more drug resistance but also more care options
While clinicians and researchers are seeing increasing numbers of HIV patients with multidrug-resistant virus, there are indications that some existing drug combinations continue to be potent against resistant virus. -
HIV-resistance evolution requires new strategies
A new study finds that 60% of HIV patients on stable therapy with detectable viral replication have a rate of new HIV mutations of about 1.5 mutations per year. -
New studies highlight HIV-resistance trends
Two separate studies have found that some types of HIV drug resistance have declined or leveled off at the same time others have increased. -
New class of inhibitor may attack resistance
There is new hope for a cost-efficient treatment for HIV-1 infected patients who no longer respond to protease inhibitor (PI) treatment due to multidrug resistance. -
Drug-resistance patterns in women discovered
If HIV-1 drug resistance is found in a womans plasma, its likely the same resistance is present in her genital tract, suggesting that drug resistance among pregnant, HIV-infected women, requires further investigation, a new study shows. -
New Congress poses challenges for advocates
No one is worried that a financially strapped federal government might kill Ryan White Care Act funding, but AIDS advocates say they are concerned about what will happen with the bill in a slightly different political environment this year. -
New microbicides enter trials in United States
Two potential candidates in the microbicide research pipeline are set to be examined in clinical trials, with research to focus on the safety and acceptability in healthy women and women infected with HIV. -
FDA Notifications
The revised Guidelines for the Use of Antiretroviral Agents in HIV-1-Infected Adults and Adolescents was made available in late October by the National Institutes of Health. The revisions were made to improve its organization and readability.